American Cancer Society
This is, without a doubt, one of the most rewarding campaigns I've worked on. On a cross country flight a woman asked me what I did; I told her I was a Creative Director. She asked me if she might have seen any of my work and I described the bowling spot. She started crying. Her mom had cancer, saw the spot, called the Cancer Society and got help. That's about as rewarding as you can get in this business. (It won a silver Effie for effectiveness.)